Skip to Main Content
Enfamil Enspire

Enspire Optimum provides our optimal nutrition with dual HMO's (2'FL & LnNT). 2'FL & LnNT helps support immune health.

New formulation with Dual HMOs (2'FL & LnNT), as well as lactoferrin, important components of breast milk.



Top Reasons to Choose Enfamil Enspire Optimum

Dual HMO (2'FL and LnNT) to support immune health. Dual HMO's found in breast milk
Has lactoferrin as an added ingredient, a key immune-supporting protein also found in breast milk
Global expert-recommended amount of Omega-3 brain building DHA
From the #1 Pediatrician recommended brand



World Health Organization recommended amount of DHA is 0.2%-0.36% of total fatty acids/ Similac=0.15% vs. Enfamil=0.32% of total fatty acids.


Learn more about important feeding topics.

Bottle-Feeding Tips for New Parents

Here are some top bottle-feeding tips to consider.
Read more

Colostrum Benefits: What is Colostrum?

Get the full breakdown on this important "first milk."


Read more



Frequently asked questions

Lactoferrin is a key immune-supporting protein found in both colostrum and breast milk. Clinical studies have confirmed the ability of Lactoferrin to support respiratory and gut health in infants and toddlers.

Yes. As with all of our infant formulas, Enfamil Enspire has been extensively reviewed by the FDA. Enspire is produced in Mead Johnson's US production facilities using domestic and internationally-sourced components.

Through our extensive research of human milk, we are able to better understand not only the nutrients in breast milk, but also the benefits of these nutrients on infants. We were able to identify two key components that are in breast milk, but largely absent from standard formulas. Because we believe these components will help support an infant's start in life, we created Enfamil® Enspire™, the only formula with Lactoferrin and MFGM added as ingredients.

Enfamil Enspire is designed for parents who want our closest formula to breast milk. Enspire has complete nutrition for any infant for whom routine formula is appropriate.

Our scientists believe that Enfamil Enspire comes closer to the nutrition in breast milk than any prior Enfamil formulation, and with its combination of ingredients, is Enfamil's best routine formula available.

Enfamil Enspire Gentlease has easy-to-digest gentle proteins and reduced lactose compared to our routine infant formulas, such as Enfamil Enspire and Enfamil® NeuroPro™ Infant. Enfamil Enspire Gentlease is designed to be easy for developing digestive systems to digest. It has has approximately 1/6 the lactose of a full-lactose, routine, milk-based infant formula.