It's always important to follow the directions on the label and to mix the proper ratio of formula to water to ensure your baby gets the right amount of nutrients. Also, since your infant doesn't yet have a strong immunity to germs, everything that comes into contact with his food—your hands, baby bottles, bottle nipples, mixing utensils, and formula scoop—should be thoroughly cleaned.

Preparing Nutramigen with Enflora LGG or PurAmino Hypoallergenic Formula1

1.  Thoroughly wash your hands with soap and water.

2.  Wash glass bottles in a dishwasher using the hot, drying cycle to sanitize and kill germs. You also can wash glass bottles and bottle nipples in hot soapy water and rinse well. Bottle nipples also can be sterilized by placing in boiling water for 5 minutes. There is no need to boil bottles.

3.  Wash and dry the top of the formula can before opening it.

4.  Pour the recommended amount of water into the sterilized bottle. If you are concerned about the safety of your tap water, use bottled water or bring cold tap water to a boil for one minute and then cool to room temperature for no more than 30 minutes before using. Otherwise, room-temperature water (not hot water!) from the tap is fine.

5.  Follow label directions to add the proper ratio of Nutramigen® or PurAmino formula to water in the bottle. Because scoop sizes vary, use only the scoop that comes with the formula. Do not water down the formula (your baby will miss out on important nutrients) or make it stronger than recommended (this can cause digestive problems) unless you are following your doctor's recommendation and are under his or her supervision.

Preparing Nutramigen with Enflora LGG2

For a 2-fluid-ounce bottle: mix 2 ounces of water with 1 packed level scoop of Nutramigen. For a 4-fluid-ounce bottle: mix 4 ounces of water with 2 packed level scoops of Nutramigen. For an 8-fluid-ounce bottle: mix 8 ounces of water with 4 packed level scoops of Nutramigen. Level off the formula powder in the scoop with a clean, dry knife.

Preparing PurAmino3

For a 2-fluid-ounce bottle: mix 2 ounces of water with 2 unpacked level scoops of PurAmino. For a 4-fluid-ounce bottle: mix 4 ounces of water with 4 unpacked level scoops of PurAmino. For an 8-fluid-ounce bottle: mix 8 ounces of water with 8 unpacked level scoops of PurAmino. Level off the formula powder in the scoop with a clean, dry knife.

6.  Securely cap the bottle. First, roll the bottle between your hands. Next, shake the bottle until the powder dissolves completely.

Transitioning from Breast to Bottle4

Whether you want to supplement your infant's breastfeeding sessions with a hypoallergenic formula such as Nutramigen with Enflora LGG or PurAmino, or are weaning your baby off breast milk entirely, you may find that your baby is more receptive to a bottle if someone else feeds him. To prepare your baby for feeding time, place a few drops of breast milk on his lips or tongue. Slowly and gently introduce the nipple into your baby's mouth. If your baby becomes frustrated or still isn't taking the bottle after 10 minutes, try again later with a mixture that is half breast milk, half formula. You may need to experiment with different nipple shapes and bottles to see what your baby prefers. Once your baby accepts the bottle, follow these feeding tips.

Feeding Nutramigen or PurAmino Formula to Your Infant5

Hold your baby in a semi-upright position with his head cradled in the crook of your arm. To keep your baby from swallowing air and getting gassy, hold the bottle so that the nipple and the neck of the bottle are always filled with formula. (Never prop a bottle. This may cause choking and increase your baby's risk of ear infections.) Gently touch the bottle nipple to your baby's cheek to stimulate the rooting reflex. If your baby gags or gulps too fast, check the nipple holes as they may be too large. If your baby is sucking hard or seems frustrated, the hole may be too small. Burp your baby several times during a feeding. Watch for signs that he is full: turning away from the bottle, releasing the bottle nipple, or falling asleep.

It's helpful to get your baby on a regular feeding schedule. Newborns typically consume 1 to 2 ounces of formula every two to three hours. One-month-old infants may consume up to 3 ounces of formula every three to four hours. From months two to six, your baby may consume an average of 4 ounces of formula every four hours. By six months, he'll probably need 6 to 8 ounces of formula four or five times a day. Essentially, your baby should be consuming about 2.5 ounces of formula for every pound of body weight.

You should continue to feed your baby Nutramigen or PurAmino formula for as long as your doctor recommends. There's no need to switch formulas if your baby takes PurAmino because it is formulated to meet the nutritional needs of infants up to 12 months, as well as toddlers up to age two.6 You should reintroduce your baby to foods made with cow's milk only while under a doctor's supervision.7

Storing Nutramigen or PurAmino Formula8

If there is formula left in the bottle after your baby's feeding and your baby won't be eating again for more than an hour, throw it out. Bacteria can flourish in leftover formula and make your baby sick.9 You can store prepared, unused formula in the refrigerator for 24 hours (never freeze it). If the prepared formula separates while in the refrigerator, shake the bottle well before use. Store cans of Nutramigen or PurAmino formula at room temperature in a dry area with the lids tightly closed. Avoid exposure to excessive heat. Do not freeze cans of formula powder. Use within one month.

Traveling with Nutramigen or PurAmino Formula10

Traveling with a baby can be taxing enough without having to worry about how you are going to feed him. Fortunately, the U.S. Transportation Security Administration (TSA) 3-ounce liquid rule for airplane carry-on luggage doesn't apply to formula or breast milk. You may bring as many prepared bottles and frozen ice packs onto a plane as needed for your journey. Keep these bottles separate from other liquids and gels, such as toothpaste and shampoo. At the security checkpoint, let the officer know that you are carrying on infant formula. Although the infant formula may be x-rayed, and you may be asked to open the bottle, neither you nor your baby will be asked to taste it. Don't forget: You can always mix water into dry formula powder after you clear security. If needed, you can warm a bottle of prepared formula by holding it under hot water. Before traveling, visit TSA for up-to-date travel rules and regulations.

*LGG is a registered trademark of Chr. Hansen A/S.


  1. AAP:; AAP:;;
  4. AAP:; AAP:; (under “feeding tips”)
  5. AAP:; AAP: NIH:
  6. PurAmino launch visual, p. 2
  7. A parent’s guide: does your baby have CMA?
  8. (under “preparation”);
  9. Nemours Foundation: (under “If formula is left over…”)
  10. TSA: